immunization

noun

im·​mu·​ni·​za·​tion ˌi-myə-nə-ˈzā-shən 

 also  i-ˌmyü-nə-

plural immunizations

: the act of making someone or something immune or the state of being immune : the act or result of immunizing someone or something: such as

a

: the production of immunity in a living organism against a disease or pathogenic agent

The plasmids used for immunization have been altered to carry genes specifying one or more antigenic proteins normally made by a selected pathogen …

—David B. Weiner et al.

also : treatment (as by vaccination) for the purpose of making an organism immune to a disease or pathogenic agent : the administration of an immune-producing substance

Measles is the single most infectious common disease—one person with measles who blunders into a crowded room will give it to almost everyone. If there were no immunization, measles would be universal.

—Wayne Biddle

Those benefits can include preventive care, such as annual physicals, immunizations, and well-baby visits.

—Consumer Reports

b

: the providing of protection or exemption from something harmful or unwanted (such as legal action)

immunization from liability

The Interior Department is negotiating with other private landowners to extend similar immunization from prosecution to those who agree to avoid activities that might hurt the bird's chances of survival.

—Ken Miller

Examples of immunization in a Sentence

Recent Examples on the Web

Though experts said it was eliminated in the U.S. in 2000, recent trends in declining childhood immunization and rising exemption claims have contributed to its resurgence. —Sonam Sheth, MSNBC Newsweek, 9 May 2025

Many American communities have immunization rates below the threshold needed for herd immunity, and the country is currently seeing the largest outbreak in over a quarter-century. —Beth Mole, ArsTechnica, 5 May 2025

Even at current immunization rates, the authors predict that measles may become endemic again and be circulating in the US within only 20 years. —Laura Baisas, Popular Science, 24 Apr. 2025

Moreover, vaccination rates for DTaP along with other childhood immunizations have been declining. —Katia Hetter, CNN Money, 1 May 2025

Word History

First Known Use

1889, in the meaning defined above

Rhymes for immunization

• abbreviation
• abomination
• acceleration
• accentuation
• accommodation
• accreditation
• acculturation
• accumulation
• acetylation
• adjudication
• administration
• adulteration

Kids Definition

immunization

noun

im·​mu·​ni·​za·​tion

ˌim-yə-nə-ˈzā-shən

: treatment (as with a vaccine) to produce immunity to a disease

Medical Definition

immunization

noun

im·​mu·​ni·​za·​tion

variants also British immunisation

ˌim-yə-nə-ˈzā-shən 

: the creation of immunity usually against a particular disease

especially : treatment (as by vaccination) of an organism for the purpose of making it immune to a particular pathogen

immunization against polio