immunization

noun

im·​mu·​ni·​za·​tion ˌi-myə-nə-ˈzā-shən 

also i-ˌmyü-nə-

plural immunizations

: the act of making someone or something immune or the state of being immune : the act or result of immunizing someone or something: such as

a

: the production of immunity in a living organism against a disease or pathogenic agent

Full immunization occurs two weeks after inoculation.

The plasmids used for immunization have been altered to carry genes specifying one or more antigenic proteins normally made by a selected pathogen …

—David B. Weiner et al.

also : treatment (as by vaccination) for the purpose of making an organism immune to a disease or pathogenic agent : the administration of an immune-producing substance

Measles is the single most infectious common disease—one person with measles who blunders into a crowded room will give it to almost everyone. If there were no immunization, measles would be universal.

—Wayne Biddle

Those benefits can include preventive care, such as annual physicals, immunizations, and well-baby visits.

—Consumer Reports

b

: the providing of protection or exemption from something harmful or unwanted (such as legal action)

immunization from liability

The Interior Department is negotiating with other private landowners to extend similar immunization from prosecution to those who agree to avoid activities that might hurt the bird's chances of survival.

—Ken Miller

Examples of immunization in a Sentence

Recent Examples on the Web

Though whooping cough vaccinations are required for Kentucky schools, only 86% of kindergartners and 85% of seventh graders are up to date with their immunization, data from the 2024-25 school immunization survey indicate. —Caroline Neal, Louisville Courier Journal, 25 Nov. 2025

And an immunization rate above 95%. —Michal Ruprecht, NPR, 21 Nov. 2025

One big reason for the divide that could be related to mandates for routine immunizations—specifically childhood vaccinations—to attend school. —Alice Park, Time, 18 Nov. 2025

Per its website, the CDC currently recommends either giving an RSV vaccine to the mother during pregnancy or an RSV immunization to infants, another preventive tool that was FDA-approved in 2023. —Alyssa Goldberg, USA Today, 17 Nov. 2025

Word History

First Known Use

1889, in the meaning defined above

Rhymes for immunization

• abbreviation
• abomination
• acceleration
• accentuation
• accommodation
• accreditation
• acculturation
• accumulation
• acetylation
• adjudication
• administration
• adulteration

Kids Definition

immunization

noun

im·​mu·​ni·​za·​tion

ˌim-yə-nə-ˈzā-shən

: treatment (as with a vaccine) to produce immunity to a disease

Medical Definition

immunization

noun

im·​mu·​ni·​za·​tion

variants also British immunisation

ˌim-yə-nə-ˈzā-shən 

: the production of immunity in a living organism against a disease or pathogenic agent

also : treatment (as by vaccination) for the purpose of making an organism immune to a disease or pathogenic agent : the administration of an immune-producing substance

immunization against polio