hyperendemic

adjective

hy·​per·​en·​dem·​ic ˌhī-pər-en-ˈde-mik How to pronounce hyperendemic (audio)
-in-
1
: exhibiting a high and continued incidence
hyperendemic malaria
2
: marked by hyperendemic disease
a hyperendemic area of tuberculosis
hyperendemicity noun
a region of hyperendemicity for dengue

Word History

First Known Use

1912, in the meaning defined at sense 2

Time Traveler
The first known use of hyperendemic was in 1912

Browse Nearby Words

Cite this Entry

“Hyperendemic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hyperendemic. Accessed 6 Feb. 2026.

Medical Definition

hyperendemic

adjective
hy·​per·​en·​dem·​ic -en-ˈdem-ik, -in- How to pronounce hyperendemic (audio)
1
: exhibiting a high and continued incidence
used chiefly of human diseases
hyperendemic malaria
2
: marked by hyperendemic disease
used of geographic areas
a hyperendemic focus of plague
hyperendemicity noun
plural hyperendemicities
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster