gastric inhibitory polypeptide

noun

variants or less commonly gastric inhibitory peptide

plural gastric inhibitory polypeptides also gastric inhibitory peptides

: an intestinal polypeptide hormone that stimulates insulin secretion by the pancreas in response to the presence of glucose in the small intestine especially following meal ingestion : glucose-dependent insulinotropic polypeptide

Researchers found that mice consuming a high-fat diet showed increased levels of gastric inhibitory polypeptide (GIP). … In the study, scientists found that excess GIP travels through the blood to the brain, where it inhibits the action of leptin—the satiety hormone. Consequently, the animals continued eating and gained weight.

—Birmingham (England) Evening Mail

—abbreviation GIP

Word History

First Known Use

1969, in the meaning defined above

Rhymes for gastric inhibitory polypeptide

• abide
• allied
• applied
• aside
• astride
• azide
• backside
• bankside
• bastide
• bayside
• bedside
• belied

Medical Definition

gastric inhibitory polypeptide

noun

variants also gastric inhibitory peptide

: an intestinal polypeptide hormone that stimulates insulin secretion by the pancreas in response to the presence of glucose in the gut especially following meal ingestion

… mice without receptors for the incretins, glucagon-like peptide 1, and gastric inhibitory polypeptide show impaired insulin secretion and abnormal glucose tolerance without insulin resistance.

—Hanna Huopio et al., The Lancet

—abbreviation GIP

called also glucose-dependent insulinotropic polypeptide