leptin

noun

lep·​tin ˈlep-tən How to pronounce leptin (audio)
: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue

Examples of leptin in a Sentence

Recent Examples on the Web It is also believed to reduce leptin levels in the body, which may additionally contribute to weight reduction. Stephen C. George, Discover Magazine, 30 Apr. 2024 Hormonal signals also act on the brain: leptin, a hormone produced by fat cells, sends signals to the hypothalamus to inhibit hunger. Andrew Chapman, Longreads, 18 Apr. 2024 But that doesn’t work for people who have developed resistance to leptin, a hormone that suppresses appetite. Karen Kaplan, Los Angeles Times, 15 Apr. 2024 Want to increase your leptin levels, suppress your appetite, and supercharge your metabolism around the clock? Amber Smith, Discover Magazine, 3 Apr. 2024 In the longer term, the hypothalamus takes cues from an appetite-suppressant called leptin. Cody Cottier, Discover Magazine, 8 Dec. 2023 And mice with lots of leptin in their bloodstreams lost weight when given Celastrol, but the compound had no effect on mice with no leptin, or in mice without any leptin receptors. K. N. Smith, Discover Magazine, 21 May 2015 This condition, known as leptin resistance, often plays a role in overeating and obesity. Cody Cottier, Discover Magazine, 8 Dec. 2023 He was spurred to leave medicine and learn about drug development by the discovery in the mid-1990s of leptin, a hormone that suppresses appetite and appeared to be a promising obesity treatment. Megan Molteni and Elaine Chen, STAT, 30 Sep. 2023

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'leptin.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

Greek leptos slender + English -in entry 1

First Known Use

1995, in the meaning defined above

Time Traveler
The first known use of leptin was in 1995

Dictionary Entries Near leptin

Cite this Entry

“Leptin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/leptin. Accessed 23 Jun. 2024.

Medical Definition

leptin

noun
lep·​tin ˈlep-tən How to pronounce leptin (audio)
: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue

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