familial hypercholesterolemia

noun

Definition of familial hypercholesterolemia 

: an inherited metabolic disorder marked by excess accumulation of LDL cholesterol in the blood resulting especially in atherosclerosis and irregular yellow skin lesions

Examples of familial hypercholesterolemia in a Sentence

Recent Examples on the Web

Xanthomas are most commonly seen in people with a genetic disease called familial hypercholesterolemia. Adam Taylor, CNN, "Heart disease risk may show in your earlobes, eyes, fingers," 29 Mar. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'familial hypercholesterolemia.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of familial hypercholesterolemia

1966, in the meaning defined above

Keep scrolling for more

Learn More about familial hypercholesterolemia

Share familial hypercholesterolemia

Resources for familial hypercholesterolemia

Statistics for familial hypercholesterolemia

Look-up Popularity

Time Traveler for familial hypercholesterolemia

The first known use of familial hypercholesterolemia was in 1966

See more words from the same year

Keep scrolling for more

More Definitions for familial hypercholesterolemia

familial hypercholesterolemia

noun

Medical Definition of familial hypercholesterolemia 

: a disorder of lipid metabolism that is caused by defective or absent receptors for LDLs on cell surfaces, that is marked by an increase in blood plasma LDLs and by an accumulation of LDLs in the body (as in connective tissue) resulting in xanthomas, atherosclerosis, and an increased risk of heart attack and coronary artery disease, and that is inherited as an autosomal dominant trait

More from Merriam-Webster on familial hypercholesterolemia

Britannica.com: Encyclopedia article about familial hypercholesterolemia

Comments on familial hypercholesterolemia

What made you want to look up familial hypercholesterolemia? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

to make faulty or ineffective

Get Word of the Day daily email!

Test Your Vocabulary

Late Autumn 2018 Words of the Day Quiz

  • frosted-autumn-leaves
  • Which is a synonym of yahoo?
How Strong Is Your Vocabulary?

Test your vocabulary with our 10-question quiz!

TAKE THE QUIZ
Dictionary Devil

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!