dysfunction

noun

dys·​func·​tion (ˌ)dis-ˈfəŋ(k)-shən 

variants or less commonly disfunction

1

: impaired or abnormal functioning

gastrointestinal dysfunction

2

: abnormal or unhealthy interpersonal behavior or interaction within a group

family dysfunction

Examples of dysfunction in a Sentence

The disease causes gastrointestinal dysfunctions.

Recent Examples on the Web

Without proper circulation, your cells wouldn’t get enough oxygen and nutrients, leading to things like health issues and/or organ dysfunction, according to the Cleveland Clinic. —Danielle Zickl, Outside, 11 Jan. 2026

The dysfunction of the franchise from ownership down is so ingrained that Saleh’s 20-36 record from 2021 and into 2024 isn’t likely to be held against him. —Jerry McDonald, Mercury News, 9 Jan. 2026

If TNF‑α loosens the blood-brain barrier, inflammatory molecules from the blood – as well as disease-causing pathogens – may have increased access to the reward circuitry of the brain, potentially worsening neuronal damage and dysfunction over time. —Habibeh Khoshbouei, The Conversation, 9 Jan. 2026

But there’s no doubting the dysfunction that comes with the streak. —Scott Thompson, FOXNews.com, 8 Jan. 2026

Word History

Etymology

dys- + function entry 1

First Known Use

circa 1916, in the meaning defined at sense 1

Phrases Containing dysfunction

• erectile dysfunction
• minimal brain dysfunction

Rhymes for dysfunction

• adjunction
• compunction
• conjunction
• disjunction
• injunction
• inunction
• malfunction
• eigenfunction
• multifunction
• function
• junction
• unction

Kids Definition

dysfunction

noun

dys·​func·​tion dis-ˈfəŋ(k)-shən 

: impaired or abnormal functioning

liver dysfunction

dysfunctional

-shnəl 

-shən-ᵊl

adjective

Medical Definition

dysfunction

noun

dys·​func·​tion

variants also disfunction

(ˈ)dis-ˈfəŋ(k)-shən 

: impaired or abnormal functioning (as of an organ of the body)

dysfunctional

-shnəl, -shən-ᵊl 

adjective

dysfunctioning

-shə-niŋ 

noun