DNA

noun

ˌdē-ˌen-ˈā 

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

• A molecular model
• 1 hydrogen
• 2 oxygen
• 3 carbon in the helical phosphate ester chains
• 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
• 5 phosphorus
• B double helix

Examples of DNA in a Sentence

Recent Examples on the Web

The team was not able to recover nuclear DNA, which would have provided more detailed information. — Katie Hunt, CNN Money, 21 Aug. 2026

Owner Mike Dew has created a pizza all his own, a hybrid of Midwest tavern-style pizza with a bit of South Shore bar pizza (popular between South Boston and Cape Cod) and Detroit-style pizza in its DNA. — Usa Today Network, USA Today, 21 Aug. 2026

To do that, researchers sequence the DNA of each patient’s tumour (by analysing samples after it’s been removed) and identify its unique mutations. — Harriet Marsden, TheWeek, 21 Aug. 2026

Martin and his colleagues think that LUCA already possessed such an encoding system in the form of nucleic acids much like modern DNA or RNA, as well as the molecular machinery to translate it to proteins. — Philip Ball, Scientific American, 20 Aug. 2026

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Phrases Containing DNA

• DNA fingerprinting
• DNA methylation
• DNA phenotyping
• DNA polymerase
• DNA test
• DNA virus
• junk DNA
• mitochondrial DNA
• recombinant DNA
• satellite DNA

Rhymes for DNA

• ay
• bay
• bey
• brae
• cay
• chez
• dey
• dray
• fay
• fey
• flay
• fray

Kids Definition

DNA

noun

ˌdē-ˌen-ˈā 

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

DNA

noun

ˌdē-ˌen-ˈā 

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna