: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

Illustration of dna
  • A molecular model
  • 1 hydrogen
  • 2 oxygen
  • 3 carbon in the helical phosphate ester chains
  • 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
  • 5 phosphorus
  • B double helix

Examples of DNA in a Sentence

Recent Examples on the Web
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Tape recovered from the bags contained razor stubble with DNA from both Melanie and William McGuire, according to the Attorney General’s Office. Stepheny Price, FOXNews.com, 1 Feb. 2026 Shortly after being assigned Porter’s case, Klein learned about fingernail clippings taken from the victim that were never tested for DNA. Colin Mixson, New York Daily News, 31 Jan. 2026 Precise placement is possible using DNA origami, which folds DNA into nanoscale shapes to guide molecules into position. Bojan Stojkovski, Interesting Engineering, 31 Jan. 2026 San Diego’s Illumina is the world leader in gene sequencing technology — the ability to read and record DNA. Noelle Harff, San Diego Union-Tribune, 30 Jan. 2026 See All Example Sentences for DNA

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Time Traveler
The first known use of DNA was in 1944

Browse Nearby Words

Cite this Entry

“DNA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/DNA. Accessed 3 Feb. 2026.

Kids Definition

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna

More from Merriam-Webster on DNA

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