: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

Illustration of dna
  • A molecular model
  • 1 hydrogen
  • 2 oxygen
  • 3 carbon in the helical phosphate ester chains
  • 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
  • 5 phosphorus
  • B double helix

Examples of DNA in a Sentence

Recent Examples on the Web
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James Watson, who co-discovered the double-helix structure of DNA in 1953, has died at age 97. Sophia Compton, FOXNews.com, 8 Nov. 2025 Under the rule, the agency could ask for facial images, iris scans, finger and palm prints, voice prints and even DNA. Jude Joffe-Block, NPR, 8 Nov. 2025 In May, more than a decade after the fingerprint match, investigators again looked at Wayne’s clothes for a DNA sample, and the Colorado Bureau of Investigation found and tested DNA on Wayne’s jeans that had a high likelihood of belonging to Saathoff. Katie Langford, Denver Post, 8 Nov. 2025 Using what was known about biology at the time and X-ray images, the two determined that DNA had a double-helix structure - like a twisted ladder, with each rung made up of a pair of chemicals. Reuters, USA Today, 7 Nov. 2025 See All Example Sentences for DNA

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Time Traveler
The first known use of DNA was in 1944

Browse Nearby Words

Cite this Entry

“DNA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/DNA. Accessed 11 Nov. 2025.

Kids Definition

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna

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