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: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

Illustration of dna
  • A molecular model
  • 1 hydrogen
  • 2 oxygen
  • 3 carbon in the helical phosphate ester chains
  • 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
  • 5 phosphorus
  • B double helix

Examples of DNA in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Moreover, the presence of all five biological nucleobases — the components of DNA and RNA — along with other findings, underscores Bennu’s significance as a repository of life’s fundamental building blocks. Mrigakshi Dixit, Interesting Engineering, 28 Nov. 2025 The busy frequency spectrum reconfigured the song’s DNA. Jazz Monroe, Pitchfork, 28 Nov. 2025 Brands are betting on buzzy ingredients such as DNA extracted from salmon or trout sperm that early research suggests may help calm or repair skin. Luke Fountain, CNBC, 27 Nov. 2025 Previous research on Bennu samples had already found 14 of the 20 amino acids all living organisms on Earth stem from, as well as all five biological nucleobases — the components that make up the genetic code in DNA and RNA. Jacopo Prisco, CNN Money, 27 Nov. 2025 See All Example Sentences for DNA

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Time Traveler
The first known use of DNA was in 1944

Browse Nearby Words

Cite this Entry

“DNA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/DNA. Accessed 3 Dec. 2025.

Kids Definition

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna

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