Definition of blot
(Entry 1 of 3)
1
: a soiling or disfiguring mark : spot
2
: a mark of reproach : moral flaw
3
: a usually nitrocellulose or nylon sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and is used to identify specific components of the spots by applying a molecular probe (such as a complementary nucleic acid or a radiolabeled antibody) — compare southern blot, western blot
blot
verb
blotted; blotting
Definition of blot (Entry 2 of 3)
1
: to spot, stain, or spatter with a discoloring substance
3a
: to dry (something, such as writing) with an absorbing agent
hastily blotted her letter
b
: to remove with absorbing material
blotting up spilled water
blot
noun (2)Definition of blot (Entry 3 of 3)
1
: a lone backgammon man exposed to capture
2
archaic
: a weak or exposed point
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Merriam-Webster unabridged
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Time Traveler for blot
The first known use of blot was in the 14th century
See more words from the same century