blot

play

noun \ˈblät\

Definition of blot

1 : a soiling or disfiguring mark : spot
2 : a mark of reproach : moral flaw
3 : a usually nitrocellulose or nylon sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and is used to identify specific components of the spots by applying a molecular probe (such as a complementary nucleic acid or a radio labeled antibody) — compare southern blot, western blot

Origin and Etymology of blot

Middle English

First Known Use: 14th century

blot

verb

Definition of blot

blotted

;

blotting

transitive verb
1 : to spot, stain, or spatter with a discoloring substance
2 obsolete : mar; especially : to stain with infamy
3a : to dry (something, such as writing) with an absorbing agent hastily blotted her letterb : to remove with absorbing material blotting up spilled water
intransitive verb
1 : to make a blot
2 : to become marked with a blot

See blot defined for English-language learners

Examples of blot in a Sentence

Don't rub the wine stain. Blot it dry with a paper towel.
Blot your lipstick with a tissue.

15th Century

First Known Use of blot

15th century

blot

noun

Definition of blot

1 : a lone backgammon man exposed to capture
2 archaic : a weak or exposed point

Origin and Etymology of blot

perhaps from Dutch bloot naked, exposed, from Middle Dutch; akin to Middle High German bloz bare

First Known Use: 1595

BLOT Defined for English Language Learners

blot

verb

Definition of blot for English Language Learners

: to dry (something, such as wet ink) by pressing a piece of cloth or paper over it

BLOT Defined for Kids

blot

play

noun \ˈblät\

Definition of blot for Students

1 : a spot or stain of dirt or ink
2 : a mark of shame or dishonor The lie was a blot on my record.

blot

play

verb

Definition of blot for Students

blotted

;

blotting

1 : ²spot 1
2 : to dry by pressing with paper or cloth

blot out

1 : to make (something) difficult to see Clouds blotted out the sun.
2 : to destroy completely No apology could blot out what I had said … — Robert Louis Stevenson, Kidnapped

Medical Dictionary

blot

play

noun \ˈblät\

Medical Definition of blot

: a nitrocellulose sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and that is used to identify specific components of the spots by applying a suitable molecular probe (as a complementary nucleic acid or a radiolabeled antibody)—see northern blot, southern blot, western blot