Definition of blot
1 : a soiling or disfiguring mark : spot
2 : a mark of reproach : moral flaw
3 : a usually nitrocellulose or nylon sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and is used to identify specific components of the spots by applying a molecular probe (such as a complementary nucleic acid or a radio labeled antibody) — compare southern blot, western blot
From the M-W Editors
Origin and Etymology of blot
Middle English
blot
Definition of blot
blotted
;blotting
transitive verb
1 : to spot, stain, or spatter with a discoloring substance
2 obsolete : mar; especially : to stain with infamy
3a : to dry (something, such as writing) with an absorbing agent hastily blotted her letterb : to remove with absorbing material blotting up spilled water
intransitive verb
1 : to make a blot
2 : to become marked with a blot
Examples of blot in a Sentence
Don't rub the wine stain. Blot it dry with a paper towel.
Blot your lipstick with a tissue.
First Known Use of blot
15th century
blot
Definition of blot
1 : a lone backgammon man exposed to capture
2 archaic : a weak or exposed point
Origin and Etymology of blot
perhaps from Dutch bloot naked, exposed, from Middle Dutch; akin to Middle High German bloz bare
BLOT Defined for English Language Learners
blot
Definition of blot for English Language Learners
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: to dry (something, such as wet ink) by pressing a piece of cloth or paper over it
BLOT Defined for Kids
Definition of blot for Students
1 : a spot or stain of dirt or ink
2 : a mark of shame or dishonor The lie was a blot on my record.
Definition of blot for Students
blotted
;blotting
1 : 2spot 1
2 : to dry by pressing with paper or cloth
blot out
1 : to make (something) difficult to see Clouds blotted out the sun.
2 : to destroy completely No apology could blot out what I had said … — Robert Louis Stevenson, Kidnapped
Medical Dictionary
blot
playMedical Definition of blot
: a nitrocellulose sheet that contains spots of immobilized macromolecules (as of DNA, RNA, or protein) or their fragments and that is used to identify specific components of the spots by applying a suitable molecular probe (as a complementary nucleic acid or a radiolabeled antibody)—see northern blot, southern blot, western blot
blot
transitive verbLearn More about blot
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See words that rhyme with blot Thesaurus: All synonyms and antonyms for blot Spanish Central: Translation of blot Nglish: Translation of blot for Spanish speakers Britannica English: Translation of blot for Arabic speakers
Seen and Heard
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