abnormality

noun

ab·​nor·​mal·​i·​ty ˌab-nər-ˈma-lə-tē 

-(ˌ)nȯr-

plural abnormalities

1

: something abnormal

2

: the quality or state of being abnormal

Synonyms of abnormality

• anomaly
• mutation

Examples of abnormality in a Sentence

The test results showed several genetic abnormalities.

There was some abnormality in his vision.

Recent Examples on the Web

In addition to chromosomal abnormalities like trisomy 21—an extra copy of chromosome 21 that causes Down syndrome—tests also scan for life-altering diseases stemming from single-gene mutations like sickle cell anemia or cystic fibrosis. —Amanda Gerut, Fortune, 29 Nov. 2025

There is not a specific treatment that is effective for Schlossberg’s specific chromosome abnormality, the doctors noted, although some new cellular therapies and immunotherapies are being investigated. —Melissa Rudy, FOXNews.com, 25 Nov. 2025

Now at age 3, Mason has been diagnosed with epilepsy — along with chromosome abnormality, anemia, developmental delay, and hypotonia, or low muscle tone. —Alexandra Phelps, Miami Herald, 24 Nov. 2025

Schlossberg's subtype —an inversion of chromosome 3 — is listed as an unfavorable abnormality of AML on the ACS website. —Kate Reilly, NBC news, 22 Nov. 2025

Word History

Etymology

abnormal entry 1 + -ity

First Known Use

1847, in the meaning defined at sense 1

Rhymes for abnormality

• cardinality
• commonality
• communality
• cordiality
• corporeality
• criminality
• criticality
• functionality
• generality
• geniality
• hospitality
• illegality

Kids Definition

abnormality

noun

ab·​nor·​mal·​i·​ty ˌab-nər-ˈmal-ət-ē 

-(ˌ)nȯr-

plural abnormalities

1

: the state of being abnormal

2

: something abnormal

Medical Definition

abnormality

noun

ab·​nor·​mal·​i·​ty ˌab-nər-ˈmal-ət-ē, -(ˌ)nȯr- 

plural abnormalities

1

: the quality or state of being abnormal

2

: something abnormal

brain-wave abnormalities