: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP) to a substrate compare protein kinase
Examples of kinase in a Sentence
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The drug, an allosteric tyrosine kinase 2 inhibitor, performed comparably to Sotyktu, a similar medicine made by Bristol Myers Squibb that was approved in 2022, FierceBiotech writes.
—
Meghana Keshavan, STAT, 11 Mar. 2024
Treatment can include monitoring the tumor (surveillance) or interventions such as surgery, chemotherapy, radiation, or medications such as tyrosine kinase inhibitors.
Surgery, which was once a primary treatment, has become less common due to high morbidity and postsurgical recurrence rates.
—Laura Hensley, Verywell Health, 13 Dec. 2023
Physicians had indeed moved their patients over to one of the newer tyrosine kinase inhibitors like Tasigna.
—WIRED, 4 Sep. 2023
But the diagnostic test, which checks to see if a patient’s tumor carries a mutation in a gene coding for anaplastic lymphoma kinase, called ALK , is just $250.
—David Ewing Duncan, Discover Magazine, 30 Oct. 2012
This change results in person's bone marrow making a specific protein called tyrosine kinase, which causes too many stem cells to become white blood cells—and, as with other types of leukemia, those extra abnormal blood cells build up, leaving less room for healthy blood cells.
—Barbara Brody, Health.com, 30 Sep. 2021
You may then be given tyrosine kinase inhibitors (TKIs), targeted therapy drugs that send signals to the cells to stop that growth.
—Gagandeep Brar, Verywell Health, 19 Mar. 2023
Tyrosine kinase inhibitors also play an important role in the treatment of medullary cancer of the thyroid.
—Christine Coppa, Health, 15 Mar. 2023
Further work showed that the ovaries of the gamergates strongly expressed a protein, Imp-L2, that ignored the MAP kinase pathway but interfered with the second pathway in the fat body.
—Viviane Callier, Quanta Magazine, 10 Jan. 2023
Meghana Keshavan, STAT, 11 Mar. 2024
Treatment can include monitoring the tumor (surveillance) or interventions such as surgery, chemotherapy, radiation, or medications such as tyrosine kinase inhibitors.
Surgery, which was once a primary treatment, has become less common due to high morbidity and postsurgical recurrence rates.
—Laura Hensley, Verywell Health, 13 Dec. 2023
Physicians had indeed moved their patients over to one of the newer tyrosine kinase inhibitors like Tasigna.
—WIRED, 4 Sep. 2023
But the diagnostic test, which checks to see if a patient’s tumor carries a mutation in a gene coding for anaplastic lymphoma kinase, called ALK , is just $250.
—David Ewing Duncan, Discover Magazine, 30 Oct. 2012
This change results in person's bone marrow making a specific protein called tyrosine kinase, which causes too many stem cells to become white blood cells—and, as with other types of leukemia, those extra abnormal blood cells build up, leaving less room for healthy blood cells.
—Barbara Brody, Health.com, 30 Sep. 2021
You may then be given tyrosine kinase inhibitors (TKIs), targeted therapy drugs that send signals to the cells to stop that growth.
—Gagandeep Brar, Verywell Health, 19 Mar. 2023
Tyrosine kinase inhibitors also play an important role in the treatment of medullary cancer of the thyroid.
—Christine Coppa, Health, 15 Mar. 2023
Further work showed that the ovaries of the gamergates strongly expressed a protein, Imp-L2, that ignored the MAP kinase pathway but interfered with the second pathway in the fat body.
—Viviane Callier, Quanta Magazine, 10 Jan. 2023
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“Kinase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/kinase. Accessed 23 Apr. 2024.
Copy CitationMedical Definition
kinase
noun
ki·nase
ˈkī-ˌnās, -ˌnāz 
: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (as ATP or ADP) to a substrate
called also phosphokinase
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