HIV

noun

ˌāch-ˌī-ˈvē 

1

: either of two retroviruses (Lentivirus humimdef1 and L. humimdef2) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

… the longer people are infected with HIV and the more immune-deficient they become, the more readily they seem to pass HIV to others.

—Robert R. Redfield et al.

Years of careful research have proven beyond doubt that the HIV virus causes AIDS, that antiretroviral drug treatment saves lives, and that the drug nevirapine is safe and effective in preventing the spread of HIV from mothers to their babies.

—Richard Marlink et al.

called also AIDS virus, human immunodeficiency virus

see also hiv-1, hiv-2

2

: the infection or disease caused by HIV

Early symptoms of HIV develop in 50 to 90 percent of people who are infected, usually beginning two to four weeks after exposure. … Because the signs and symptoms of … HIV may be similar to other common illnesses, such as mononucleosis, most people do not initially realize that they have HIV.

—Paul E. Sax

Examples of HIV in a Sentence

Recent Examples on the Web

According to the Telegraph, the move marks Prince Harry's final break with Sentebale, the NGO that Harry himself co-founded in 2006 to support orphans and young people affected by HIV in Lesotho and Botswana. — Diego Parrado, Vanity Fair, 16 Aug. 2026

Certain Human Immunodeficiency Virus (HIV) Medications Certain HIV medications are associated with kidney damage. — Karen Berger, Verywell Health, 14 Aug. 2026

Amiri Kabuye, a nurse who helps oversee HIV care in Kasensero, says just 60 people received 6 months of protection at the town's only health clinic. — Michal Ruprecht, NPR, 13 Aug. 2026

Jones does not have HIV, and the text message did not come from Equality Florida. — Raisa Habersham, Miami Herald, 11 Aug. 2026

Word History

First Known Use

1986, in the meaning defined at sense 1

Phrases Containing HIV

• anti-HIV

Kids Definition

HIV

noun

ˌāch-ˌī-ˈvē 

: any of a group of viruses that infect and destroy helper T cells causing the marked reduction in their numbers that is diagnostic of AIDS

Medical Definition

HIV

noun

ˌā-ˌchī-ˈvē 

1

: either of two retroviruses (Lentivirus humimdef1 and L. humimdef2) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

called also AIDS virus, human immunodeficiency virus

see also hiv-1, hiv-2

2

: the infection or disease caused by HIV