: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

Illustration of dna
  • A molecular model
  • 1 hydrogen
  • 2 oxygen
  • 3 carbon in the helical phosphate ester chains
  • 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
  • 5 phosphorus
  • B double helix

Examples of DNA in a Sentence

Recent Examples on the Web
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The medication stops the replication of hepatitis B DNA in the body, halving the risk of liver cancer and other complications. Jia H. Jung, Mercury News, 1 Sep. 2025 The new species was identified by its DNA, glands, body size, coloring, body proportions and other subtle physical features, the study said. Aspen Pflughoeft, Miami Herald, 1 Sep. 2025 These are small, identifiable pieces of DNA that are already known to influence key traits like coat color, body structure, locomotion, and behavior. Rupendra Brahambhatt, Interesting Engineering, 31 Aug. 2025 The Clyffe is positioned as a revolutionary hybrid, merging high-performance climbing footwear DNA with the effortless style of an everyday sneaker. Cassell Ferere, Forbes.com, 31 Aug. 2025 See All Example Sentences for DNA

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Time Traveler
The first known use of DNA was in 1944

Browse Nearby Words

Cite this Entry

“DNA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/DNA. Accessed 4 Sep. 2025.

Kids Definition

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna

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