: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

Illustration of dna
  • A molecular model
  • 1 hydrogen
  • 2 oxygen
  • 3 carbon in the helical phosphate ester chains
  • 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
  • 5 phosphorus
  • B double helix

Examples of DNA in a Sentence

Recent Examples on the Web
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Now, the juxtapositions that are so key to Charli’s style DNA manifest in Anthony Vaccarello’s current athleisure-meets-lingerie looks. Alice Newbold, Vogue, 12 Jan. 2026 Researchers are also banking DNA, creating a kind of reef edition of Noah’s Ark. Susan Casey, Travel + Leisure, 10 Jan. 2026 The broad strokes have been well-known — the ticking of a woman’s biological clock increases risk of miscarriage and infertility, often caused by eggs with the wrong number of chromosomes, the structures that carry DNA. Carolyn Y. Johnson, Washington Post, 9 Jan. 2026 But slowing down was built into the DNA of Rental Family. Aaron Couch, HollywoodReporter, 8 Jan. 2026 See All Example Sentences for DNA

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Time Traveler
The first known use of DNA was in 1944

Browse Nearby Words

Cite this Entry

“DNA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/DNA. Accessed 13 Jan. 2026.

Kids Definition

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna

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