Cooley's anemia

noun

Coo·ley's anemia | \ ˈkü-lēz-

Definition of Cooley's anemia

: an inherited disorder of hemoglobin synthesis that is the most severe form of beta-thalassemia, is marked by severe anemia associated with deficient hemoglobin, the presence of microcytes, and accelerated red cell destruction, and is associated with enlargement of the liver and spleen, an increase in erythroid bone marrow, bone deformities, and poor growth rate

Note: Cooley's anemia is inherited as an autosomal recessive trait requiring that both parents pass on a copy of the defective gene located on the chromosome numbered 11. Cooley's anemia occurs especially in individuals of Mediterranean ancestry and necessitates regular blood transfusions throughout life.

Keep scrolling for more

Learn More about Cooley's anemia

Dictionary Entries near Cooley's anemia

Statistics for Cooley's anemia

Look-up Popularity

Time Traveler for Cooley's anemia

The first known use of Cooley's anemia was in 1934

See more words from the same year

Keep scrolling for more

More Definitions for Cooley's anemia

Cooley's anemia

noun

Coo·ley's anemia | \ ˌkü-lēz-

variants: also Cooley's disease

Medical Definition of Cooley's anemia

: an inherited disorder of hemoglobin synthesis that is the most severe form of beta-thalassemia, is marked by severe anemia associated with deficient hemoglobin, the presence of microcytes, and accelerated red cell destruction, and is associated with enlargement of the liver and spleen, an increase in the erythroid bone marrow, bone deformities, and poor growth rate

— called also beta-thalassemia major, thalassemia major