1
as in wrong
falling short of a standard
the milk tasted off
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2
as in dormant
not being in a state of use, activity, or employment
the computer is off, so you'll have to turn it on in order to use it
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3
as in erroneous
not being in agreement with what is true
that claim that everyone is actually related to everyone else seems a bit off
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4
as in small
small in degree
on the off chance that you do get straight A's, you can skip a grade
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5
as in spicy
hinting at or intended to call to mind matters regarded as indecent
a telltale smirk suggested that there was something off about his parting shot
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as in to assassinate
to put to death deliberately
the hit man was rumored to have offed at least three people in the last year alone
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Merriam-Webster unabridged
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