excruciation

a state of great suffering of body or mind had never experienced such excruciation as when he contracted shingles Synonyms affliction, agony, anguish, distress, hurt, misery, pain, rack, strait(s), torment, torture, travail, tribulation, woeRelated Words discomfort; cross, crucible, trial; heartache, heartbreak, joylessness, sadness, sorrow, unhappiness; emergency, pinch; asperity, difficulty, hardship, rigor; ache, pang, smarting, soreness, stitch, throe, twinge; danger, jeopardy, troubleNear Antonyms comfort, consolation, solace; alleviation, assuagement, ease, relief; peace, security; well-being