How to Use off-label in a Sentence

off-label

adjective
  • They are not approved for weight loss but can be prescribed off-label by doctors.
    ABC News, 23 Feb. 2023
  • In fact, 1 in 5 prescriptions is for off-label use of a drug.
    Naomi Cahn, The Conversation, 15 May 2026
  • Instead, a healthcare provider may prescribe medicines for off-label use.
    Sarah Fielding, Health.com, 20 Sep. 2021
  • That waiver applies even when a treatment is unproven or off-label.
    Cindy Krischer Goodman, Sun Sentinel, 5 Mar. 2026
  • Few weight-loss drugs have been approved for older children, although many are used off-label.
    The Editors, Scientific American, 13 June 2023
  • While it is not yet approved for weight loss, it might be used off-label for obesity—and soon to be approved for it.
    Laura Hensley, Verywell Health, 21 Mar. 2023
  • That means doctors have to be familiar enough with the hormone to prescribe it off-label.
    Rachel E. Gross, The Atlantic, 17 Apr. 2024
  • But then doctors began using them off-label to take weight off and then things really got hot for them.
    David Sherer, Baltimore Sun, 14 Apr. 2024
  • The drug is often prescribed for off-label use to treat a range of pain conditions, studies show.
    Melissa Rudy, FOXNews.com, 21 May 2025
  • Doctors can still prescribe it for weight loss as an off-label medication.
    Amber Smith, Discover Magazine, 25 Sep. 2023
  • Even though leucovorin is not approved to treat autism, doctors can prescribe it off-label.
    Aria Bendix, NBC news, 10 Mar. 2026
  • But it is also often used off-label for breast cancer prevention.
    Laura Hensley, Verywell Health, 29 Nov. 2023
  • Doctors can prescribe medicines off-label, and in rare disease that happens often.
    Brad Quick, CNBC, 27 Mar. 2026
  • Other forms of semaglutide, meanwhile, have been prescribed off-label for weight-loss treatment as well.
    Stephen C. George, Discover Magazine, 30 Apr. 2024
  • But off-label prescribing is common in medicine, and legal for physicians.
    Theresa Gaffney, STAT, 6 Mar. 2026
  • That’s why a health care professional should supervise this off-label use.
    Joe Graedon, M.s., and Teresa Graedon, oregonlive, 13 Mar. 2023
  • Ozempic and Mounjaro are being prescribed off-label for weight loss.
    Laura Hensley, Verywell Health, 12 June 2023
  • This article will discuss how physicians are using it off-label.
    Leslie Baumann, Miami Herald, 30 Jan. 2024
  • That’s why it’s being used off-label around the world to treat people with a variety of mental health issues.
    Soph Warnes, CNN Money, 28 Sep. 2025
  • Which is why some are prescribing it off-label as a daily moisturizer.
    Hannah Baxter, Robb Report, 18 June 2024
  • It’s considered an off-label treatment.
    Nicole Hernandez, USA Today, 3 Apr. 2026
  • Current buzz around semaglutide namely stems from its off-label use, primarily for weight loss.
    Sarah Sloat, Health, 30 Mar. 2023
  • People who don’t fall into these categories may still be able to get a vaccine if a provider is willing to give it off-label.
    Brenda Goodman, CNN Money, 19 Sep. 2025
  • As such, off-label use of Zepbound and Mounjaro may pose patient safety risks.
    Melissa Rudy, FOXNews.com, 10 Sep. 2025
  • For a while, these off-label prescriptions were getting covered without any issues.
    Ed Silverman, STAT, 3 Aug. 2023
  • While these are not specifically approved for use in the jawline, many injectors do use them off-label to sculpt this area.
    Petra Guglielmetti, Glamour, 18 Sep. 2023
  • Its off-label use also has placed ketamine in a medical and legal gray area, Alexander said.
    Tribune News Service, Hartford Courant, 3 June 2024
  • While minoxidil is not a cure for TE, it has been used off-label for this condition.
    Jessica Swirble, Verywell Health, 10 July 2025
  • Trazodone is an antidepressant that is used off-label for insomnia.
    Jessica Swirble, Verywell Health, 17 Sep. 2025
  • Some insurers cover off-label uses of GLP drugs while many do not.
    Daniel Gilbert, Anchorage Daily News, 12 June 2023

Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'off-label.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

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