oxycodone

noun

oxy·​co·​done ˌäk-sē-ˈkō-ˌdōn How to pronounce oxycodone (audio)
: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride

Examples of oxycodone in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Cathy believes that Daveigh's addiction began when she was prescribed oxycodone and other painkillers after injuring her back in a motorcycle accident around 2016. Wesley Stenzel, Entertainment Weekly, 20 June 2026 Experts say this puts unsuspecting users seeking more common drugs, such as oxycodone, fentanyl, or stimulants like cocaine, at risk of fatal overdoses. Jonathan Moens — Bellingcat, STAT, 18 June 2026 Many patients use an opioid medication, such as oxycodone, to deal with the discomfort, though some are fine with just extra-strength Tylenol. Michele Promaulayko, Allure, 17 June 2026 Authorities say fentanyl can be sold as pills with some online dealers claiming the pills are Xanax, Percocet and oxycodone. Rosalio Ahumada, Sacbee.com, 16 June 2026 See All Example Sentences for oxycodone

Word History

Etymology

oxy + codeine + -one

First Known Use

1963, in the meaning defined above

Time Traveler
The first known use of oxycodone was in 1963

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Cite this Entry

“Oxycodone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/oxycodone. Accessed 27 Jun. 2026.

Medical Definition

oxycodone

noun
oxy·​co·​done -ˈkō-ˌdōn How to pronounce oxycodone (audio)
: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride C18H21NO4·HCl to relieve moderate to severe pain

Note: Oxycodone is marketed under the trademarks OxyContin, Percocet, and Percodan.

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