: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride

Examples of oxycodone in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In the cases of Perry and Miller, prosecutors ultimately secured convictions for the people who supplied Perry with ketamine and Miller with cocaine and oxycodone pills laced with fentanyl. Richard Winton, Los Angeles Times, 14 Sep. 2026 That year, the head trainer of the Commanders was found to have been illegally distributing oxycodone to players — an unsettling reminder of the NFL's difficult history with painkillers. ABC News, 28 Aug. 2026 More recently came a 2020 investigation of the head trainer for the Washington Commanders for illegally distributing oxycodone to players. Joshua Goodman, Fortune, 28 Aug. 2026 The different doctors who did not adopt a holistic approach, and in fact did not even speak with each others, the prescription of oxycodone for neck pain to a woman whose liver was already failing are some the examples that led to her demise. Dr. Shaheena Janjuha-Jivraj, Forbes.com, 21 Aug. 2026 See All Example Sentences for oxycodone

Word History

Etymology

oxy + codeine + -one

First Known Use

1963, in the meaning defined above

Time Traveler
The first known use of oxycodone was in 1963

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Cite this Entry

“Oxycodone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/oxycodone. Accessed 17 Sep. 2026.

Medical Definition

oxycodone

noun
: a narcotic analgesic C18H21NO4 used especially in the form of its hydrochloride C18H21NO4·HCl to relieve moderate to severe pain

Note: Oxycodone is marketed under the trademarks OxyContin, Percocet, and Percodan.

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