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or·bi·to·fron·tal | \ ˌȯr-bit-ə-ˈfrənt-ᵊl 
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\Medical Definition of orbitofrontal
: located in, supplying, or being the part of the cerebral cortex in the basal region of the frontal lobe near the orbit the orbitofrontal branch of the middle cerebral artery orbitofrontal blood flow the orbitofrontal cortex
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