neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive ˌnu̇r-ō-di-ˈje-nə-rə-tiv 

-ˈjen-rə-;

-ˈje-nə-ˌrā-;

-dē-,

ˌnyu̇r-

: relating to or marked by degeneration of nervous tissue

Examples of neurodegenerative in a Sentence

Recent Examples on the Web

Doug McConnell, a 67-year-old Chicago-area native who lost both his father and sister to the neurodegenerative disease, founded the organization in 2011. —Melina Khan, USA Today, 22 Sep. 2025

The website receives about 770,000 page views each month from scientists working around the world on developing personalized therapies for rare cancers, modeling human neurodegenerative diseases and screening drug candidates for conditions like Alzheimer’s. —Evan Bush, NBC news, 15 Sep. 2025

Dane, 52, has spoken candidly about his journey with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the motor neurons in the brain and spinal cord. —Jessica Wang, Entertainment Weekly, 15 Sep. 2025

Dudley said further research needed could include seeing if the shift observed also occurs in other neurodegenerative or inflammatory conditions. —Hannah Millington, MSNBC Newsweek, 12 Sep. 2025

Word History

First Known Use

1907, in the meaning defined above

Rhymes for neurodegenerative

• degenerative
• regenerative
• generative

Medical Definition

neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive -di-ˈjen-ə-ˌrāt-iv, -di-ˈjen-(ə-)rət- 

: relating to or characterized by degeneration of nervous tissue

neurodegeneration

-di-ˌjen-ə-ˈrā-shən, -ˌdē- 

noun