neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive ˌnu̇r-ō-di-ˈje-nə-rə-tiv 

-ˈjen-rə-;

-ˈje-nə-ˌrā-;

-dē-, 

ˌnyu̇r-

: relating to or marked by degeneration of nervous tissue

Examples of neurodegenerative in a Sentence

Recent Examples on the Web

The finding has the potential to provide a longer runway to make the lifestyle changes that can help reduce risk, and could be used to better identify subjects who could benefit from participating in clinical trials seeking to prevent or treat neurodegenerative disease. —Paul Sisson, San Diego Union-Tribune, 12 Mar. 2026

The role of inflammation While cardiovascular health has the most supporting data, large-scale studies have also linked sauna use to lower rates of respiratory illness and even some neurodegenerative conditions like dementia and Alzheimer's. —Will Stone, NPR, 6 Mar. 2026

These conditions, such as movement disorders and neurodegenerative diseases like Parkinson's disease, often impair essential functions like movement, speech, and swallowing, leading to a profound loss of independence. —CBS News, 5 Mar. 2026

The call focused on the FDA’s decision to ask for an additional clinical trial from the biotechnology company UniQure before greenlighting it to apply for approval of its gene therapy for Huntington’s disease, a fatal neurodegenerative disorder. —Meg Tirrell, CNN Money, 5 Mar. 2026

Word History

First Known Use

1907, in the meaning defined above

Phrases Containing neurodegenerative

• neurodegenerative disease
• neurodegenerative disorder

Rhymes for neurodegenerative

• degenerative
• regenerative
• generative

Medical Definition

neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive -di-ˈjen-ə-ˌrāt-iv, -di-ˈjen-(ə-)rət- 

: relating to or characterized by degeneration of nervous tissue

neurodegeneration

-di-ˌjen-ə-ˈrā-shən, -ˌdē- 

noun