neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive ˌnu̇r-ō-di-ˈje-nə-rə-tiv 

-ˈjen-rə-;

-ˈje-nə-ˌrā-;

-dē-, 

ˌnyu̇r-

: relating to or marked by degeneration of nervous tissue

Examples of neurodegenerative in a Sentence

Recent Examples on the Web

In March, biotech company uniQure said the agency asked for an additional clinical trial of an experimental gene therapy for the fatal neurodegenerative disorder Huntington’s disease, dashing hopes of patients and advocates who’d hoped for a faster path to approval. —Sarah Owermohle, CNN Money, 8 May 2026

The actor had publicly revealed nearly one year earlier that he had been diagnosed with ALS, also known as Lou Gehrig’s disease, a progressive neurodegenerative illness that affects nerve cells and muscle function. —Deirdre Durkan, PEOPLE, 8 May 2026

Some theories suggest that moly could have been the snowdrop (Galanthus nivalis), which has properties that inhibit enzymes linked to neurodegenerative disorders. —Gitanjali Roy, Encyclopedia Britannica, 30 Apr. 2026

As an anti-inflammatory, curcumin may improve joint pain, neurodegenerative conditions, and allergies. —Lindsay Curtis, Health, 28 Apr. 2026

Word History

First Known Use

1907, in the meaning defined above

Phrases Containing neurodegenerative

• neurodegenerative disease
• neurodegenerative disorder

Rhymes for neurodegenerative

• degenerative
• regenerative
• generative

Medical Definition

neurodegenerative

adjective

neu·​ro·​de·​gen·​er·​a·​tive -di-ˈjen-ə-ˌrāt-iv, -di-ˈjen-(ə-)rət- 

: relating to or characterized by degeneration of nervous tissue

neurodegeneration

-di-ˌjen-ə-ˈrā-shən, -ˌdē- 

noun