Medical Definition of hypermutable
: exhibiting or capable of excessive mutation or change Another severe obstacle for those with compromised immune systems: the hypermutable bacteria that can be found in cystic fibrosis patients. These chameleon-like germs produce numerous mutations when they replicate, creating more potential possibilities for drug resistance.—Jim Doyle, The Birmingham (Alabama) News, 9 Oct. 2013
hypermutability\-ˌmyüt-ə-ˈbil-ət-ē\ play noun “What we've found,” he [Kenneth Kinzler] explained, “is a subtle alteration in the genetic code that causes DNA instability and leads to hypermutability, or a cascade of mutations in surrounding genes.”—Newsday (Melville, New York), 26 Aug. 1997
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