hydrocodone

noun

hy·​dro·​co·​done ˌhī-drō-ˈkō-ˌdōn 

: a habit-forming compound that is derived from codeine and is administered in the form of its bitartrate C₁₈H₂₁NO₃·C₄H₆O₆ usually in combination with other drugs (as acetaminophen) as an analgesic or cough suppressant

Examples of hydrocodone in a Sentence

Recent Examples on the Web

Prescription opioids, such as oxycodone, hydrocodone and morphine, are commonly prescribed after a surgery, including C-sections. —Kaylin Klie, The Conversation, 26 Feb. 2026

Gipson acknowledged the hydrocodone bottle recovered from the home was not tested for fentanyl and testified that no drug paraphernalia was found. —Stepheny Price, FOXNews.com, 26 Feb. 2026

The sheriff's office said she was taken into custody on several warrants for trafficking cocaine, trafficking fentanyl, trafficking hydrocodone, and cocaine sales as well as several charges of drug possession and drug paraphernalia possession, among other charges. —Steven Yablonski, CBS News, 24 Feb. 2026

Fentanyl is a synthetic opioid and is included in data related to hydrocodone, oxycodone, methadone, morphine and heroin-related deaths. —Kyle Werner, Des Moines Register, 9 Feb. 2026

Word History

First Known Use

1964, in the meaning defined above

Rhymes for hydrocodone

• anyone
• everyone
• megaton
• overdone
• overrun
• povidone
• trazodone
• begun
• grandson
• gudrun
• handgun
• homespun

Medical Definition

hydrocodone

noun

hy·​dro·​co·​done ˌhī-drō-ˈkō-ˌdōn 

: a habit-forming compound derived from codeine and administered in the form of its bitartrate C₁₈H₂₁NO₃·C₄H₆O₆ usually in combination with other drugs (as acetaminophen) as an analgesic or cough sedative

called also dihydrocodeinone

see hycodan, vicodin