epigenetic

adjective

epi·​ge·​net·​ic ˌe-pə-jə-ˈne-tik How to pronounce epigenetic (audio)
1
a
: of, relating to, or produced by the chain of developmental processes in epigenesis that lead from genotype to phenotype after the initial action of the genes
b
: relating to, being, or involving changes in gene function that do not involve changes in DNA sequence
epigenetic inheritance
2
of a deposit or structure : formed after the laying down of the enclosing rock
epigenetically adverb

Examples of epigenetic in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Programs begin with biological age testing, genetic profiling, and epigenetic analysis, followed by personalized protocols for cellular renewal and preventive health. Meggen Harris, Forbes.com, 28 Aug. 2025 In Long Story Short, Judaism is religious, but it’s as often treated as cultural, mystical and epigenetic, a series of practices and traditions that connect a disjointed people to happiness and trauma, that bring comfort and discomfort alike. Daniel Fienberg, HollywoodReporter, 22 Aug. 2025 This suggests that obesity before pregnancy can change epigenetic marks in the mother’s eggs, which in turn alter how certain brain genes work in the next generation. New Atlas, 16 Aug. 2025 The study's evidence that the epigenetic clock can be slowed in an invertebrate raises the possibility that environmental factors—or eventually medical interventions—might one day delay biological aging in humans. Thomas Westerholm, MSNBC Newsweek, 15 Aug. 2025 See All Example Sentences for epigenetic

Word History

Etymology

epi- + genetic, after epigenesis

First Known Use

1883, in the meaning defined at sense 1a

Time Traveler
The first known use of epigenetic was in 1883

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Cite this Entry

“Epigenetic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/epigenetic. Accessed 7 Sep. 2025.

Medical Definition

epigenetic

adjective
epi·​ge·​net·​ic -jə-ˈnet-ik How to pronounce epigenetic (audio)
1
: of, relating to, or produced by epigenesis
the epigenetic nature of vertebrate development
2
: relating to, being, or involving a modification in gene expression that is independent of the DNA sequence of a gene
epigenetic carcinogenesis
epigenetic inheritance
Methylation is one of many epigenetic signals—chemical changes to DNA and its associated proteins—that modify gene activity without altering the genetic information itself.Tina Hesman Saey, Science News
epigenetically adverb
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