1
: development of a plant or animal from an egg or spore through a series of processes in which unorganized cell masses differentiate into organs and organ systems
also : the theory that plant and animal development proceeds in this way compare preformation sense 2
2
: change in the mineral character of a rock owing to outside influences

Examples of epigenesis in a Sentence

Recent Examples on the Web
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Some species, indeed, can pass this resilience on to their offspring by a process called intergenerational epigenesis. — The Economist, 15 Mar. 2018 Disease researchers, Francis reports, have hopes that the effects of abnormal epigenesis may be reversed. — Razib Khan, Discover Magazine, 20 June 2011

Word History

Etymology

borrowed from New Latin (William Harvey), from epi- epi- + genesis genesis

First Known Use

1798, in the meaning defined at sense 1

Time Traveler
The first known use of epigenesis was in 1798

Browse Nearby Words

Cite this Entry

“Epigenesis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/epigenesis. Accessed 1 Oct. 2026.

Medical Definition

epigenesis

noun
1
: development involving gradual diversification and differentiation of an initially undifferentiated entity (as a zygote or spore) compare preformation
2
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