path·​o·​gen·​e·​sis ˌpa-thə-ˈje-nə-səs How to pronounce pathogenesis (audio)
: the origination and development of a disease

Examples of pathogenesis in a Sentence

Recent Examples on the Web That’s because the mucous membranes that line these structures can serve as staging grounds for microbial pathogenesis, the process by which microbes cause disease. Sabrina Sholts, Smithsonian Magazine, 12 Mar. 2024 For example, basic research has focused on identifying long Covid laboratory markers and the pathogenesis (mechanism) linking the virus with the symptoms. Steven Phillips, STAT, 14 Sep. 2023 In this study, Golden et al. demonstrated both in cell culture and in mice that mitochondrial antiviral signaling protein (MAVS) activation along with cytokine production contribute to the pathogenesis of Crimean-Congo Hemorrhagic Fever Virus, identifying key new targets for potential treatments. William A. Haseltine, Forbes, 3 June 2022 The three species share nearly identical biology, pathogenesis and clinical pathology. Rebecca Kreston, Discover Magazine, 10 Apr. 2011 These impact viral characteristics including replication efficiency, pathogenesis, and virulence. William A. Haseltine, Forbes, 6 July 2022 Once inside the body, the coronavirus invades the epithelial cells that line and protect the respiratory tract, said Taubenberger, who heads the viral pathogenesis and evolution section of the National Institute of Allergy and Infectious Diseases in Bethesda, Maryland. Jason Gale, Fortune, 8 Mar. 2020 Resources For more information on the molecular structure and pathogenesis of HPV, there’s a public-access PDF from 1993 that’s helpful but mostly focuses on cervical strains. Rebecca Kreston, Discover Magazine, 17 Oct. 2011 His interpretation of the pathogenesis of syphilis was unconventional, however his hypothesis was formed by means of what would eventually become his literary trademark - the observation of natural phenomena and the power of logical reasoning. Rebecca Kreston, Discover Magazine, 1 Dec. 2015

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'pathogenesis.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


patho- + genesis, after French pathogénésie, German Pathogenese

First Known Use

1850, in the meaning defined above

Time Traveler
The first known use of pathogenesis was in 1850

Dictionary Entries Near pathogenesis

Cite this Entry

“Pathogenesis.” Dictionary, Merriam-Webster, Accessed 22 May. 2024.

Medical Definition


patho·​gen·​e·​sis ˌpath-ə-ˈjen-ə-səs How to pronounce pathogenesis (audio)
plural pathogeneses -ˌsēz How to pronounce pathogenesis (audio)
: the origination and development of a disease

called also pathogeny

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