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: being or occurring in the final stages of a terminal disease or condition
end-stage renal disease

Examples of end-stage in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Despite the use of medications to treat dilated, weak hearts, some patients suffer from continued weakening of the heart muscle and progress to end-stage, or advanced, heart failure. William Cornwell, The Conversation, 19 Nov. 2025 Dialysis can keep a person with end-stage kidney disease alive, but the process can be hard on the body and can typically sustain someone for only about five years, on average. Jen Christensen, CNN Money, 13 Nov. 2025 At least two patients have died after transplantation, although doctors say these patients were terminal and were experiencing end-stage kidney disease. Mary Kekatos, ABC News, 13 Nov. 2025 Lisa Vanderpump’s family is coping with heartbreaking news after her 28-year-old nephew was diagnosed with end-stage liver disease. Vivian Kwarm, Mercury News, 29 Oct. 2025 See All Example Sentences for end-stage

Word History

First Known Use

1920, in the meaning defined above

Time Traveler
The first known use of end-stage was in 1920

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Cite this Entry

“End-stage.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/end-stage. Accessed 1 Dec. 2025.

Medical Definition

end-stage

adjective
: being or occurring in the final stages of a terminal disease or condition
end-stage liver failure
Last Updated: - Updated example sentences
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