dependence

noun

de·​pen·​dence di-ˈpen-dən(t)s 

variants or less commonly dependance

1

: the quality or state of being dependent

especially : the quality or state of being influenced or determined by or subject to another

2

: reliance, trust

3

: one that is relied on

4

a

: drug addiction

developed a dependence on painkillers

b

: habituation sense 2b

Synonyms of dependence

• dependency
• reliance

Examples of dependence in a Sentence

The company was hurt by its dependence on government loans.

Our dependence upon foreign oil makes our economy vulnerable.

a harmful dependence on foreign oil

Recent Examples on the Web

That will give defensive coordinator Zach Orr more options with his pressure packages and perhaps create less dependence on blitzes to harass the quarterback. —Jeff Zrebiec, New York Times, 5 Nov. 2025

The deal allows OpenAI to move away from its sole dependence on Microsoft, its biggest investor and until recently its only cloud provider. —Tom Chivers, semafor.com, 4 Nov. 2025

The college experience was marked by rupture, the sometimes messy yet necessary transition from dependence to independence. —Russell Shaw, The Atlantic, 2 Nov. 2025

The two also unveiled a new framework on rare earths, aimed at reducing dependence on China’s near-monopoly over critical resources. —Betsy Klein, CNN Money, 31 Oct. 2025

Word History

Etymology

Middle English dependaunce, borrowed from Anglo-French dependence, dependance, from dependant dependent entry 1 + -ence, -ance -ence, -ance

First Known Use

15th century, in the meaning defined at sense 1

Phrases Containing dependence

• linear dependence
• self-dependence

Rhymes for dependence

• ascendance
• attendance
• dependance
• transcendence
• interdependence
• superintendence
• tendance

Kids Definition

dependence

noun

de·​pend·​ence

di-ˈpen-dən(t)s

1

: the quality or state of being dependent

especially : the quality or state of being influenced by or subject to another

2

: reliance sense 2, trust

3

: something on which one relies

4

: a drug addiction

Medical Definition

dependence

noun

de·​pen·​dence di-ˈpen-dən(t)s 

1

: the quality or state of being dependent upon or unduly subject to the influence of another

2

a

: drug addiction

b

: habituation sense 2b