creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

Taking creatine may also make therapy or antidepressants more effective; in one study, women taking an antidepressant plus creatine had twice the remission rate than those taking the medication with a placebo. —Cindy Kuzma, SELF, 28 May 2025

They may not be sold next to standard supplements like magnesium and creatine in stores, but they’re practically being put on the same shelf by the upper echelons of Hollywood. —Kaleigh Werner, Footwear News, 22 May 2025

Taking creatine supplements boosts brain creatine stores, which may positively affect cognitive function and memory. —Jillian Kubala, Health, 29 Apr. 2025

Both brands advise taking a five-gram scoop of creatine a day. —Devinder Bains, Glamour, 16 May 2025

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine