Medical Dictionary

catenin

noun ca·te·nin \ ˈka-tə-nən, kə-ˈtē- \

medical Definition of catenin

:any of various intracellular, cytoplasmic proteins that mediate the adhesion of one cell to another by connecting the actin microfilaments of one cell's cytoskeleton to the transmembrane cadherins of another cell
  • Vascular-endothelium cadherins are coupled intracellularly to catenins, a family of proteins that form signaling complexes with downstream kinases and phosphatases.
  • —Ralph L. Nachman et al.The New England Journal of Medicine18 Sept. 2008
Note: Specific catenins are designated with the prefixes alpha- (or α-), beta- (or β-), etc.
  • Beta-catenin normally helps to form junctions with neighboring cells.
  • —Ricki L. RustingScientific AmericanJune 2001

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