cadherin

noun
cad·her·in | \ kad-ˈhir-ən \

Medical Definition of cadherin 

: any of various glycoproteins that mediate the calcium-dependent adhesion of cells to other cells

Note: Cadherins are composed of polypeptide chains that typically extend through the cell membrane and have a large extracellular part which forms a binding domain. They are usually bound by cadherins present on adjacent cells.

The X-ray crystallography showed that adjacent cadherins on the same cell would tend to form pairs. Furthermore, the tip of a cadherin from a neighboring cell would fit neatly between the two members of a pair, forming chemical bonds with both. —Josie Glausiusz, Discover, September 1995 Cadherins are critical mediators of metazoan cell adhesion and signaling and provide the structural basis for vital developmental processes, including tissue morphogenesis and maintenance, cell sorting, and cell polarization … —Monika Abedin et al., Science, 15 Feb. 2008

Learn More about cadherin

Dictionary Entries near cadherin

cade

cade oil

caderas

cadherin

cadmium

cadmium sulfide

caduceus

Comments on cadherin

What made you want to look up cadherin? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

an open space surrounded by woods

Get Word of the Day daily email!

Test Your Vocabulary

Name that Food Quiz

How Strong Is Your Vocabulary?

Test your vocabulary with our 10-question quiz!

TAKE THE QUIZ
Syn City

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!