medical Definition of autophagosome
- The autophagosome does not bud off from preexisting organelles but, rather, is formed by a dynamic process of membrane expansion.
- —Daniel J. Klionsky, The New England Journal of Medicine, 23 Apr. 2009
- During autophagy, a portion of cytoplasm is sequestered into an autophagosome: this then fuses with the lysosome, and the cytoplasm-derived materials are degraded.
- —Satoshi Tsukamoto et al., Science, 4 July 2008