autophagosome

noun
au·​to·​phago·​some | \ ˌȯ-tō-ˈfag-ə-ˌsōm How to pronounce autophagosome (audio) \

Medical Definition of autophagosome

: a double membrane-bound vesicle that encloses cellular constituents and fuses with lysosomes which digest these cellular constituents during autophagy The autophagosome does not bud off from preexisting organelles but, rather, is formed by a dynamic process of membrane expansion.— Daniel J. Klionsky, The New England Journal of Medicine During autophagy, a portion of cytoplasm is sequestered into an autophagosome: this then fuses with the lysosome, and the cytoplasm-derived materials are degraded.— Satoshi Tsukamoto et al., Science

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Dictionary Entries Near autophagosome

auto-oxidation

autophagosome

autophagy

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Cite this Entry

“Autophagosome.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/autophagosome. Accessed 2 Oct. 2022.

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