antagonize

verb

an·​tag·​o·​nize an-ˈta-gə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing

transitive verb

1
: to incur or provoke the hostility of
His criticism antagonized his friends.
2
: to act in opposition to : counteract
The drug is antagonized by methylxanthines, such as caffeine and theophylline …Scientific American Medicine

Examples of antagonize in a Sentence

He didn't mean to antagonize you. Her comments antagonized many people.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The bill intends to take away some of the policing power from the Securities and Exchange Commission, widely considered as Wall Street's cop — but which had antagonized the crypto sector under the Biden administration. Rafael Nam, NPR, 19 July 2025 Wish-casting a better result for a confrontation in a different place, Vindman suppresses how much and how often America antagonized Russia through its idealist actions, rather than realist inaction. Samuel Moyn, Harpers Magazine, 16 July 2025 With Mexico also being subject to U.S. tariffs, Mexican President Claudia Sheinbaum Pardo has antagonized Trump but done so in a way that has earned Trump’s favor. David Zimmermann, The Washington Examiner, 8 July 2025 Oh, Caitlin can clap at ya now, Caitlin can antagonize ya now. Ryan Gaydos, FOXNews.com, 19 June 2025 See All Example Sentences for antagonize

Word History

Etymology

Greek antagōnizesthai, from anti- + agōnizesthai to struggle, from agōn contest — more at agony

First Known Use

circa 1742, in the meaning defined at sense 2

Time Traveler
The first known use of antagonize was circa 1742

Browse Nearby Words

Cite this Entry

“Antagonize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonize. Accessed 23 Jul. 2025.

Kids Definition

antagonize

verb
an·​tag·​o·​nize an-ˈtag-ə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
: to stir up dislike or anger in

Medical Definition

antagonize

transitive verb
an·​tag·​o·​nize
variants also British antagonise
antagonized also British antagonised; antagonizing also British antagonising
: to act in antagonism to : counteract
these effects are antagonized by atropineErnest Bueding & Harry Most

More from Merriam-Webster on antagonize

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!