antagonize

verb

an·​tag·​o·​nize an-ˈta-gə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing

transitive verb

1
: to incur or provoke the hostility of
His criticism antagonized his friends.
2
: to act in opposition to : counteract
The drug is antagonized by methylxanthines, such as caffeine and theophylline …Scientific American Medicine

Examples of antagonize in a Sentence

He didn't mean to antagonize you. Her comments antagonized many people.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The White House, which has reversed initiatives supporting LGBTQ+ people, particularly those who are transgender, has shown a willingness to hammer corporations that antagonize it. Jessica Guynn, USA Today, 7 May 2025 Why are Republicans antagonizing a Republican governor? DeSantis hasn’t enjoyed the scrutiny from his fellow Republicans. Kirby Wilson, Miami Herald, 1 May 2025 Many international trips are booked months in advance, and can be hard to cancel, and so even a traveller who feels antagonized by U.S. policies may in the end get on a plane anyway. Josh Holder, New York Times, 30 Apr. 2025 His reign was not perfect, and his liberal creed antagonized enough conservative Catholics that a counter-movement has emerged in the U.S., complete with its own conferences, private schools and publications. Gustavo Arellano, Los Angeles Times, 23 Apr. 2025 See All Example Sentences for antagonize

Word History

Etymology

Greek antagōnizesthai, from anti- + agōnizesthai to struggle, from agōn contest — more at agony

First Known Use

circa 1742, in the meaning defined at sense 2

Time Traveler
The first known use of antagonize was circa 1742

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Cite this Entry

“Antagonize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonize. Accessed 14 May. 2025.

Kids Definition

antagonize

verb
an·​tag·​o·​nize an-ˈtag-ə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
: to stir up dislike or anger in

Medical Definition

antagonize

transitive verb
an·​tag·​o·​nize
variants also British antagonise
antagonized also British antagonised; antagonizing also British antagonising
: to act in antagonism to : counteract
these effects are antagonized by atropineErnest Bueding & Harry Most

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