Medical Definition of alloimmunized
: having undergone isoimmunization Alloimmunized patients can be extremely difficult to treat with platelet transfusions; the likelihood of finding HLA-matched donors is often limited, and maneuvers to blunt the antibody response or interfere with immune destruction have been unsuccessful.—Margot S. Kruskall, The New England Journal of Medicine, 25 Dec. 1997
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