alloimmunization

noun
al·​lo·​im·​mu·​ni·​za·​tion | \ ˌa-lō-ˌi-myə-nə-ˈzā-shən, -ˌnī-ˈzā- also -i-ˌmyü-nə- \

Medical Definition of alloimmunization 

: isoimmunization Transfusions are effective in preventing many complications of sickle cell disease, but the iron overload and alloimmunization that result from repeated transfusions can complicate treatment.— Miguel R. Abboud, The New England Journal of Medicine, 10 Dec. 2009

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