alloimmune

adjective
al·lo·im·mune | \ ˌal-ō-i-ˈmyün \

Medical Definition of alloimmune 

: of, relating to, or characterized by isoimmunization Various studies over the past decade have indicated that the alloimmune response, mediated by anti-HLA antibodies, plays a key role in the failure of kidney allografts; this concept has been extended to heart, lung, and composite tissue transplants. —Alexandre Loupy et al., The New England Journal of Medicine, 26 Sept. 2013

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occurring twice a year or every two years

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