Medical Dictionary
Müllerian inhibiting substance
Mullerian inhibiting substance
alsomüllerian inhibiting substance
ormullerian inhibiting substance
Medical Definition of Müllerian inhibiting substance
: a glycoprotein hormone produced by the Sertoli cells of the male testis during fetal development that causes regression and atrophy of the Müllerian ducts : anti-mullerian hormone—abbreviation MIS
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Biographical Note for müllerian inhibiting substance
Müller
, Johannes Peter
(1801–1858), German physiologist and anatomist. Müller is generally acclaimed as one of the greatest biologists of all time. In 1834–40 he published a handbook of physiology that ranks as the first great text on that subject produced in the 19th century. In histology he described the microscopic anatomy of a large series of secreting glands. He was the first to classify the excretory system of the glands as an independent system of tubes; he noted that the blood vessels formed only a capillary network. He described the Müllerian duct in 1825.
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