5-alpha-reductase

noun
5-al·​pha-re·​duc·​tase
variants: also 5α-reductase \ ˈfīv-​ˈal-​fə-​ri-​ˈdək-​ˌtās, -​ˌtāz How to pronounce 5α-reductase (audio) \

Medical Definition of 5-alpha-reductase

: an enzyme that catalyzes the conversion of testosterone to dihydrotestosterone

Note: Drugs (such as finasteride) are sometimes used to inhibit 5-alpha-reductase in the treatment of benign prostatic hyperplasia. A deficiency of 5-alpha-reductase causes the genetic disorder 5-alpha-reductase deficiency.

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Cite this Entry

“5-alpha-reductase.” The Merriam-Webster.com Medical Dictionary, Merriam-Webster Inc., https://www.merriam-webster.com/medical/5-alpha-reductase. Accessed 9 December 2019.

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