Medical Dictionary

5-alpha-reductase

noun 5-al·pha-re·duc·tase
variants: also 5α-reductase play \ˈfīv-ˈal-fə-ri-ˈdək-ˌtās, -ˌtāz\

medical Definition of 5-alpha-reductase

: an enzyme that catalyzes the conversion of testosterone to dihydrotestosterone
Note: Drugs (such as finasteride) are sometimes used to inhibit 5-alpha-reductase in the treatment of benign prostatic hyperplasia. A deficiency of 5-alpha-reductase causes the genetic disorder 5-alpha-reductase deficiency.

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