Medical Dictionary

5–alpha–reductase

noun 5–al·pha–re·duc·tase
variants: also

5α–reductase

\ˈfīv-ˈal-fə-ri-ˈdək-ˌtās, -ˌtāz\ play

Medical Definition of 5–alpha–reductase

  1. :  an enzyme that catalyzes the conversion of testosterone to dihydrotestosterone Drugs (such as finasteride) are sometimes used to inhibit 5-alpha-reductase in the treatment of benign prostatic hyperplasia. A deficiency of 5-alpha-reductase causes the genetic disorder 5-alpha-reductase deficiency.


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