1
: not opposed
an unopposed invasion
: having no opponent
a politician who is running for election unopposed
2
medical : being or relating to estrogen replacement therapy in which a progestin (such as medroxyprogesterone acetate) is not coadministered to reduce the potential risks (such as endometrial cancer) associated with estrogen used alone
A woman who has had her uterus removed can take the estrogen "unopposed"—that is, without the addition of progestin.Consumer Reports

Examples of unopposed in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
District 36 Incumbent candidate Lynn Melton, a Democrat who has served District 36 since 2023, ran unopposed in the primary. Sofi Zeman, Kansas City Star, 5 Aug. 2026 Those two unopposed re-elections were instead approved by acclamation, a process that installed Infantino for another four years without the need for a ballot. Philip Buckingham, New York Times, 4 Aug. 2026 The new district now stretches from Kansas City through the suburbs into the more rural parts of the state, and Cleaver is running unopposed for the Democratic nomination. Caroline Linton, CBS News, 4 Aug. 2026 Infantino was reelected unopposed in 2019 in Paris and 2023 in Kigali, Rwanda. Graham Dunbar, Fortune, 2 Aug. 2026 See All Example Sentences for unopposed

Word History

First Known Use

1625, in the meaning defined at sense 1

Time Traveler
The first known use of unopposed was in 1625

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Cite this Entry

“Unopposed.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/unopposed. Accessed 9 Aug. 2026.

Medical Definition

unopposed

adjective
: being or relating to estrogen replacement therapy in which a progestin (as medroxyprogesterone acetate) is not coadministered to reduce the potential risks (as endometrial cancer) associated with estrogen used alone
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