unopposed

adjective

un·​op·​posed ˌən-ə-ˈpōzd 

1

: not opposed

an unopposed invasion

: having no opponent

a politician who is running for election unopposed

2

medical : being or relating to estrogen replacement therapy in which a progestin (such as medroxyprogesterone acetate) is not coadministered to reduce the potential risks (such as endometrial cancer) associated with estrogen used alone

A woman who has had her uterus removed can take the estrogen "unopposed"—that is, without the addition of progestin.

—Consumer Reports

Examples of unopposed in a Sentence

Recent Examples on the Web

The other five were unopposed races. —Katie Campione, Deadline, 4 Sep. 2025

Japan was virtually unopposed in the air, able to bomb Chinese cities at will. —Brad Lendon, CNN Money, 1 Sep. 2025

Candidates running with the support of the Caucus for elective office often run unopposed in the municipal elections. —Daniel I. Dorfman, Chicago Tribune, 30 Aug. 2025

Trump's backing cleared the prospective field instantly and Gruters ran unopposed. —Brittany Shepherd, ABC News, 22 Aug. 2025

Word History

First Known Use

1625, in the meaning defined at sense 1

Rhymes for unopposed

• misdiagnosed
• overexposed
• superimposed
• undecomposed
• apposed
• bulldozed
• composed
• deposed
• disclosed
• disposed
• enclosed
• exposed

Medical Definition

unopposed

adjective

un·​op·​posed -ə-ˈpōzd 

: being or relating to estrogen replacement therapy in which a progestin (as medroxyprogesterone acetate) is not coadministered to reduce the potential risks (as endometrial cancer) associated with estrogen used alone