Definition of trypanosome
: any of a genus (Trypanosoma) of parasitic flagellate protozoans that infest the blood of various vertebrates including humans, are usually transmitted by the bite of an insect, and include some that cause serious diseases (such as sleeping sickness and Chagas disease)
Medical Definition of trypanosome
: any flagellate of the genus Trypanosoma
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Britannica.com: Encyclopedia article about trypanosome
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