testosterone

noun

tes·​tos·​ter·​one te-ˈstä-stə-ˌrōn 

1

: a hormone that is a hydroxy steroid ketone C₁₉H₂₈O₂ produced especially by the testes or made synthetically and that is responsible for inducing and maintaining male secondary sex characters

2

: qualities (such as brawn and aggressiveness) usually associated with males : manliness

Examples of testosterone in a Sentence

Recent Examples on the Web

The generalizations about the use and effectiveness of testosterone are at best premature. —Lauryn Higgins, Flow Space, 6 Nov. 2025

She was also subjected to harassment over her gender and was one of four players barred from the 2022 Women’s Africa Cup of Nations over testosterone levels. —Doha Madani, NBC news, 4 Nov. 2025

The statement defended Orlando Pride striker Barbra Banda, who was ruled ineligible to compete for Zambia in a 2022 World Cup-qualifying tournament after a test revealed Banda's natural testosterone levels were above those allowed by the Confederation of African Football. —Jackson Thompson, FOXNews.com, 4 Nov. 2025

Researchers found key reproductive hormones estrogen, progesterone and testosterone in hard tissues, such as the bones and teeth, of skeletons dating back as far as 1,000 years, according to a study published October 2 in the Journal of Archaeological Science. —Jack Guy, CNN Money, 31 Oct. 2025

Word History

Etymology

borrowed from German Testosteron, from Latin testēs testes + German -o- -o- + -steron -sterone

Note: The name was introduced by the Hungarian pharmacologists Karoly Gyula David (1905-45) and János Freud (1901-48), the Dutch endocrinologist Elisabeth Dingemanse (1886-1952), and the German-born Dutch physician and pharmacologist Ernst Laqueur (1880-1947) (all affiliated with the Pharmaco-Therapeutic Laboratory of the University of Amsterdam) in "Über krystallinisches männliches Hormon aus Hoden (Testosteron), wirksamer als aus Harn oder aus Cholesterin bereitetes Androsteron," Zeitschrift für physiologische Chemie, Band 233 (1935), pp. 281-83.

First Known Use

1935, in the meaning defined at sense 1

Rhymes for testosterone

• aldosterone
• anticyclone
• progesterone
• acetone
• anglophone
• baritone
• bourguignon
• buspirone
• chaperon
• chaperone
• cobblestone
• collarbone

Kids Definition

testosterone

noun

tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn 

: a male hormone produced by the testes that causes the development of the male reproductive system and secondary sex characteristics

Medical Definition

testosterone

noun

tes·​tos·​ter·​one te-ˈstäs-tə-ˌrōn 

: a male hormone that is a crystalline hydroxy steroid ketone C₁₉H₂₈O₂ produced primarily by the testes or made synthetically and that is the main androgen responsible for inducing and maintaining male secondary sex characteristics see androgel, axiron