Definition of take a flier
US, informal
: to do something that could have either good or bad results : to gamble on something risky
He took a flier in politics soon after getting his degree.
—often + on Investors have been unwilling to take a flier on such a small and unproven company.
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“Take a flier.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/take%20a%20flier. Accessed 20 May. 2022.
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