synergistic

adjective

syn·​er·​gis·​tic ˌsi-nər-ˈji-stik 

1

: having the capacity to act in synergism

synergistic drugs

2

: of, relating to, or resembling synergism

a synergistic reaction

synergistically

ˌsi-nər-ˈji-sti-k(ə-)lē 

adverb

Examples of synergistic in a Sentence

Recent Examples on the Web

And the next speech was Frederick Douglass, who was very synergistic with Lincoln. — Dana Taylor, USA Today, 1 June 2026

Some supplements, such as melatonin, L-theanine, and tryptophan, may have an additive or synergistic effect on sleep when taken with magnesium. — Emmanuella Ogbonna, Health, 17 June 2026

That eating pattern delivers omega-3s, polyphenols, B vitamins and antioxidants from whole food sources alongside fiber and synergistic compounds that isolated pills can’t replicate. — Allison Palmer, Sacbee.com, 7 May 2026

Although these appeared to be synergistic acquisitions, the cost structures, regulatory exposure, and margin profile showed otherwise. — Brian Delp, Forbes.com, 29 June 2026

Word History

First Known Use

1832, in the meaning defined at sense 1

Rhymes for synergistic

• agonistic
• altruistic
• animistic
• aphoristic
• atheistic
• atomistic
• cabalistic
• calvinistic
• chauvinistic
• dualistic
• egoistic
• egotistic

Kids Definition

synergistic

adjective

syn·​er·​gis·​tic ˌsin-ər-ˈjis-tik 

: of, relating to, or able to act in synergism

synergistic drugs

Medical Definition

synergistic

adjective

syn·​er·​gis·​tic ˌsin-ər-ˈjis-tik 

1

: having the capacity to act in synergism

synergistic drugs

synergistic muscles

2

: of, relating to, or resembling synergism

a synergistic reaction

a synergistic effect

synergistically

-ti-k(ə-)lē 

adverb