syn·​er·​gist ˈsi-nər-jist How to pronounce synergist (audio)
: something (such as a chemical or a muscle) that enhances the effectiveness of an active agent
broadly : either member of a synergistic pair

Examples of synergist in a Sentence

Recent Examples on the Web Evans had a friendly synergist at The New Yorker, where Brown serialized works by Monica Crowley, Edward Jay Epstein and other Random House authors. Hillel Italie, USA TODAY, 24 Sep. 2020 The vinegar also seemed to act as a synergist to help all the other ingredients be more available and effective. Howard Garrett, Dallas News, 18 June 2019

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'synergist.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1870, in the meaning defined above

Time Traveler
The first known use of synergist was in 1870

Dictionary Entries Near synergist

Cite this Entry

“Synergist.” Dictionary, Merriam-Webster, Accessed 26 Sep. 2023.

Medical Definition


syn·​er·​gist -jəst How to pronounce synergist (audio)
: an agent that increases the effectiveness of another agent when combined with it
especially : a drug that acts in synergism with another
: an organ (as a muscle) that acts in concert with another to enhance its effect compare agonist sense 1, antagonist sense a
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