sucralose

noun

su·​cra·​lose ˈsü-krə-ˌlōs How to pronounce sucralose (audio)
: a white crystalline powder C12H19Cl3O3 that is derived from sucrose and is used as a low-calorie sweetener having a sweetness of much greater intensity than sucrose

Examples of sucralose in a Sentence

Recent Examples on the Web
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The team used mouse models to show the negative impacts of sucralose are driven by disruption to gut bacteria. Hannah Millington, MSNBC Newsweek, 31 July 2025 Not everyone, however, may feel the combined effects of sucralose in the same way, Katz said. Sandee Lamotte, CNN Money, 29 Mar. 2025 Of these, some are poorly absorbed (sucralose), others are metabolized quickly (aspartame), and some are excreted in urine (acesulfame potassium, or ace-k), which may influence metabolic pathways differently. New Atlas, 29 July 2025 In girls, consumption of glycyrrhizin, sucralose and added sugars was linked to a higher risk of central precocious puberty. Daniella Gray, MSNBC Newsweek, 13 July 2025 See All Example Sentences for sucralose

Word History

Etymology

probably from sucrose + -al entry 3 + -ose entry 2

First Known Use

1985, in the meaning defined above

Time Traveler
The first known use of sucralose was in 1985

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Cite this Entry

“Sucralose.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sucralose. Accessed 30 Aug. 2025.

Medical Definition

sucralose

noun
su·​cra·​lose ˈsü-krə-ˌlōs How to pronounce sucralose (audio)
: a white crystalline powder C12H19Cl3O8 that is derived from sucrose by the chemical substitution of three chlorine atoms for three hydroxyl groups and that is used as a low-calorie sweetener having a sweetness of much greater intensity than sucrose
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