substrate

noun

sub·​strate ˈsəb-ˌstrāt 

1

: substratum

2

: the base on which an organism lives

the soil is the substrate of most seed plants

3

: a substance acted upon (as by an enzyme)

Did you know?

With its Latin prefix sub-, "below", substrate obviously refers to a layer under something else. Rock may serve as the substrate for the coral in a coral reef. Tiny wafers of silicon (or another semiconductor) serve as the substrate for computer chips. Substrate may also mean subsoil—that is, the layer under the topsoil, lacking in organic matter or humus. Substrate is part of the vocabulary of various other sciences, including chemistry and biology. But although it's mostly a scientific term, writers may also use it to mean simply "foundation"—for instance, when observing that reading is the substrate on which most other learning is based.

Examples of substrate in a Sentence

Recent Examples on the Web

Citi also called out opportunities in advanced glass packaging substrates for next-generation semiconductor applications, as well as its solar component business ramping and becoming a tailwind to earnings. — Jeff Marks, CNBC, 13 July 2026

The center dome is manufactured using a chemical vapor deposition process, where diamond is grown as a crystalline layer before the substrate is removed, leaving a self-supporting diamond dome. — Mark Sparrow, Forbes.com, 10 July 2026

It can even be mounted on flexible substrates like plastic or fabric. — Mrigakshi Dixit, Interesting Engineering, 9 July 2026

Rather than placing optical chiplets beside processors, the company is building a photonic interposer that serves as the packaging substrate itself. — IEEE Spectrum, 9 July 2026

Word History

Etymology

Medieval Latin substratum

First Known Use

1730, in the meaning defined at sense 1

Rhymes for substrate

• abate
• airfreight
• await
• baseplate
• berate
• birthdate
• birthrate
• bookplate
• borate
• breastplate
• bromate
• casemate

Kids Definition

substrate

noun

sub·​strate ˈsəb-ˌstrāt 

1

: an underlying layer: as

a

: substratum sense a

b

: the base on which an organism lives or over which it moves

the soil is the substrate of most plants

2

: a substance acted upon (as by an enzyme)

Medical Definition

substrate

noun

sub·​strate ˈsəb-ˌstrāt 

1

: substratum sense 1

2

: the base on which an organism lives

3

: a substance acted upon (as by an enzyme)