Definition of substance
- possession of a controlled substance
- substance abuse
- a family of substance
The pancreas secretes a substance called insulin.
The floor was covered with a white, powdery substance that turned out to be flour.
heroin and other illegal substances
He had a history of substance abuse.
When has he ever said anything of substance?
The results of the study give substance to their theory.
the substance of my argument
These example sentences are selected automatically from various online news sources to reflect current usage of the word 'substance.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.
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