sterilize

verb

ster·​il·​ize ˈster-ə-ˌlīz 

sterilized; sterilizing

transitive verb

: to make (something or someone) sterile: such as

a

: to free from all viable microorganisms (as by the use of steam or dry heat)

sterilize surgical instruments in an autoclave

b(1)

: to deprive of the power of reproducing through surgery

sterilize cats and dogs

(2)

: to make incapable of germination

studied the effects of sterilizing wheat florets

c

: to cause (land) to become unfruitful

There, 1,100-degree pyroclastic flows had sterilized the land.

—Christine Colasurdo

Examples of sterilize in a Sentence

The organization encourages people to sterilize their cats and dogs.

Recent Examples on the Web

It was meant to sterilize camels but had a stimulating effect on women 16 to 32. —Niela Orr, Vulture, 13 Jan. 2026

Select a pair of sharp secateurs to take your cuttings and sterilize the blades with rubbing alcohol or a 10% bleach solution. —Lauren Landers, The Spruce, 10 Jan. 2026

Also, be sure to sterilize pruners used to make the cuts between palms. —Tom MacCubbin, The Orlando Sentinel, 10 Jan. 2026

The most popular cleaning methods for a menstrual cup include cleaning it with natural products like baking soda or castile soap, submerging it in a sterilizing solution like the type used for baby bottles or boiling it for five to 10 minutes. —Bestreviews, Mercury News, 7 Jan. 2026

Word History

First Known Use

1676, in the meaning defined above

Phrases Containing sterilize

• pre-sterilize

Rhymes for sterilize

• advertise
• aggrandize
• agonize
• alibis
• alkalies
• alkalis
• amortize
• amplifies
• analyse
• analyze
• anywise
• authorize

Kids Definition

sterilize

verb

ster·​il·​ize ˈster-ə-ˌlīz 

sterilized; sterilizing

: to make sterile: as

a

: to deprive of the power of reproduction

had their cat sterilized

b

: to free of microscopic living things and especially germs (as bacteria)

sterilize the dental instruments

sterilization

ˌster-ə-lə-ˈzā-shən 

noun

Medical Definition

sterilize

transitive verb

ster·​il·​ize

variants also British sterilise

ˈster-ə-ˌlīz 

sterilized also British sterilised; sterilizing also British sterilising

: to make sterile:

a

: to deprive of the power of reproducing

b

: to free from living microorganisms (as by the use of physical or chemical agents)

sterilize a surgical instrument

sterilization

ˌster-ə-lə-ˈzā-shən 

noun

also British sterilisation

-ˌlī-ˈ